Christian McCaffrey Best Prop Bets for 49ers vs. Buccaneers on Sunday 10/12/25

The news content focuses on Charlie Cummings' analysis of Christian McCaffrey's prop bets for the San Francisco 49ers versus the Tampa Bay Buccaneers game, highlighting both teams' strong 4-1 records and their status as NFC contenders. McCaffrey is emphasized as a central figure in the matchup, with prop bets centered around his performance drawing significant attention.

McCaffrey has been handling an extensive workload this season, averaging 18 carries and 8 receptions per game over five games, serving as a consistent force amid the 49ers' offensive struggles due to injuries. However, his yards per carry have dropped to a career low of 3.1, largely because defenses are stacking the box to limit his running game and challenge backup quarterback Mac Jones to make plays instead.

This strategy could prove problematic against the Buccaneers' stout front seven, which features elite run stoppers like Vita Vea and Lavonte David, making it one of the toughest challenges McCaffrey has faced this season. The analysis suggests that while the 49ers have found ways to win, their ground game has not been the primary solution and is unlikely to improve in this specific matchup.