Cubs at White Sox Prediction: Odds, expert picks, starting pitchers, betting trends, and stats for July 25

The Chicago Cubs (60-42) will face the Chicago White Sox (37-66) at Rate Field in Chicago, IL on Friday, July 25, 2025, starting at 7:40 PM EST. Cubs pitcher Shota Imanaga is scheduled to start against White Sox pitcher Adrian Houser.

Entering the game, the Cubs are struggling with a 1-3 record in their last four games, including losing two out of three games against the Royals in their previous series. Conversely, the White Sox are performing strongly in the second half of the season, boasting a 5-1 record and securing series wins against both the Tampa Bay Rays and the Pittsburgh Pirates.

The preview promises detailed information and analysis for the matchup, covering how to watch the first pitch, the betting odds, recent team performance, relevant player statistics, and predictions, picks, and best bets generated by modeling tools and expert staff.

The game will be broadcast or streamed on MARQ and CHSN. Viewers are also directed to follow Rotoworld Player News for ongoing fantasy and betting news and analysis.