Bettors making massive mistake with Eagles-Cowboys matchup in Week 1

Betting activity for the Week 1 matchup between the Philadelphia Eagles and Dallas Cowboys in the 2025 NFL season shows significant interest in the underdog Cowboys despite the Eagles being favored by 7 points. According to BetMGM data, the Cowboys at +7 are the most-bet team in ticket volume for Week 1 and rank second in total handle. Additionally, the Cowboys' +260 moneyline is the most-bet underdog wager in ticket count. This game is the most-bet matchup of opening week by tickets, while the point total is the second-most-bet on Overs.

This betting trend persists despite the Eagles' overwhelming dominance in their 2024 matchups, where Philadelphia won 34-6 at Dallas in November and 41-7 at home in December. The Eagles outscored the Cowboys 75-13 across both games, with Dallas showing minimal competitiveness regardless of quarterback Dak Prescott's health. Historically, the series was balanced before 2024, with each team winning alternately—the Cowboys took the 2021 season series, but Philadelphia claimed the last five years' overall advantage with their 2024 sweep.

Bettors appear drawn to the Cowboys' potential for higher payouts, though the Eagles present strong counterarguments: Philadelphia has won three consecutive home games against Dallas, finished 14-3 last season, and won the Super Bowl, while Dallas had a 7-10 record. Despite the betting public's lean toward Dallas, the article suggests the Eagles remain the analytically safer choice for wagers, even with lower potential returns.